The other interesting thing to consider is the induced signal in the speaker from the Mac's transformer could be very partially fed back to the input via the NFB loop and it could be modulated somewhat, depending on the fluctuations in the field due to currents flowing in all the channels whilst playing robust content.
I don't blame the McIntosh at all and it's not faulty IMO. Plenty of amplifiers have stray radiated fields from large transformers. Back in the vinyl and tape deck days, much time and effort was spent by me and millions of other audiophiles, carefully arranging HiFi components to ensure their transformers didn't induce noises in EQs, cassette decks and turntables. Knowing where the transformers were and moving things from right to left in cabinets, spacing and order of stacking was extremely important. But to get it in a unconnected loudspeaker is pretty awesome in my book.
You should simply move the amplifier to the other side of the cabinet, that will cut down the noise significantly I would expect, as the TXF is further away from the speaker and its internals (depending on where the inductors are inside), or preferably into its own cabinet or stand. You bought a beast of an amp and its letting you know that. I think you should also reach out to McIntosh service department and relate your experience- see what they have to say.
I remember once, years ago putting a loudspeaker on top of an amplifier I was testing and heard what I thought was a buzz in the unconnected speaker. I blamed the magnet assembly and the top panel of the amp and promptly forgot about it. I'll bet it was the same thing, but I dismissed it at the time as "impossible".
I've definitely had sensitive headphones that have picked up radiated mains and the concept is the same- but they were terminated.
Your experience,
@ClassG33, encouraged me to investigate and work out just WTF was happening in your case.
If anyone wants some analyzer FFTs of the induced mains in the centre speaker drivers, from the toroidal in my pics I can do that in the morning? It is just a proof of concept that it could happen and be audible, not indicative of the OP's actual severity.