Totally, sound is affected by the room. Its more useful to think other way around, you listen sound in room that speakers put in there. You are listening the room not speakers, unless you get the speakers close enough so that direct sound is much louder than room sound. Room modes are subsection of all the effects room has to sound, first reflections, flutter echo, spectral balance of early reflections and how long reverberance there is and so on. Then there is psychoacoustics, how sound is perceived, and all of it changes with frequency.
As sound is invisible its helpful to try and connect it to something more tangible which helps to imagine and understand it better. For example blink of an eye lasts about tenth of a second, 100ms. If two walls in your room are 5 meters apart sound travels between the two walls roughly 7 times during eye blink! As there is typically six boundaries on a room and sound reflects spectacularly number of reflections that hit ear within the eye blink are calculated in thousands. Its amazing how hearing system can weed out the message from the bombardment. There is difference how early reflections within few milliseconds affect perceived sound compared to late reverberance, direction and content of early reflections matter and so on.
Another, 5 meters is wavelength of 68Hz. There would be modes between these two boundaries 5 meters apart from half wavelength and multiples of (in frequency). Pressure minima center of the distance at 34Hz, maxima 68Hz and so on. Height of a room could be 2.5 meters making modes between floor and ceiling from 68Hz and multiples of. Basically sound of bass is dominated by room and how speakers and observation point are positioned in there, and it is just not deep bass but all the way up to kick bass >100Hz and beyond the smaller the room is. Size of the room defines density of the modes, the bigger the room the denser they become (closer in frequency). At some particular frequency tied to room size modes get so dense they are now called reverberation, this is called Schroeder frequency. Modes are easiest to visualize on computer, this example was to illustrate wavelength is the glue between sound to physical world, it ties how speakers and room interact and how you perceive it.
I hope this gets your imagination rolling. Its best to read on acoustics, plenty of books and web resources to read. Have fun!